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2011  
月日 担当者 Paper
2月 29日

Jaepel J, Blum R: Capturing ER calcium dynamics. Eur J Cell Biol 90: 613-619, 2011

2月 27日

田端

Hirose T, Totsune K, Mori T, Morimoto R, Metoki H, Asayama K, Kikuya M, Ohkubo T, Kohzuki M, Takahashi K, Imai Y: Expression of adrenomedullin 2/intermedin, a possible reno-protective peptide, is decreased in the kidneys of rats with hypertension or renal failure. Am J Physiol Renal Physiol 299: F128-134, 2010

2月 23日

海藤

Kawakami H, Kamiie J, Yasuno K, Kobayashi R, Aihara N, Shirota K: Dynamics of absolute amount of nephrin in a single podocyte in puromycin aminonucleoside nephrosis rats calculated by quantitative glomerular proteomics approach with selected reaction monitoring mode. Nephrol Dial Transplant. doi: 101093/ndt/gfr492, 2011

2月2日 宮原

[論文1] Kharbanda KK, Vigneswara V, McVicker BL, Newlaczyl AU, Bailey K, Tuma D, Ray DE, Carter WG: Proteomics reveal a concerted upregulation of methionine metabolic pathway enzymes, and downregulation of carbonic anhydrase-III, in betaine supplemented ethanol-fed rats. Biochem Biophys Res Commun 381: 523-527, 2009
[論文2] Caballero VJ, Mendieta JR, Giudici AM, Crupkin AC, Barbeito CG, Ronchi VP, Chisari AN, Conde RD: Alternation between dietary protein depletion and normal feeding cause liver damage in mouse. J Physiol Biochem 67: 43-52, 2011

1月26日 重村

Fougeray S, Bouvier N, Beaune P, Legendre C, Anglicheau D, Thervet E, Pallet N: Metabolic stress promotes renal tubular inflammation by triggering the unfolded protein response. Cell Death Dis. 2011 doi: 10. 1038/cddis. 2011. 26

1月19日 押川

Wang Z, Hill S, Luther JM, Hachey DL, Schey KL: Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). Proteomics 12. 1-10, 2011

12月 15日 髙橋

Chiang CK, Tanaka T, Inagi R, Fujita T, Nangaku M: Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner. Lab Invest. 91: 1564-1571, 2011

12月 8日 園田

Siedlecki A, Irish W, Brennan DC: Delayed graft function in the kidney transplant. Am J Transplant 11: 2279-96, 2011

12月 8日 池田

ER stress and InsP3 receptor
<論文1>Higo T, Hamada K, Hisatsune C, Nukina N, Hashikawa T, Hattori M, Nakamura T, Mikoshiba K: Mechanism of ER stress-induced brain damage by IP3 receptor. Neuron 68: 865-878, 2010
<論文2>Higo T, Hattori M, Nakamura T, Natsume T, Michikawa T, Mikoshiba K: Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44. Cell 120: 85-98, 2005

11月24日

Santoso NG, Cebotaru L, Guggino WB: Polycystin-1, 2, and STIM1 interact with IP3R to modulate ER Ca2+ release through thePI3K/Akt pathway. Cell Physiol Biochem 27: 715-726, 2011

11月17日 田端

Niu P, Shindo T, Iwata H, Iimuro S, Takeda N, Zhang Y, Ebihara A, Suematsu Y, Kangawa K, Hirata Y, Nagai R: Protective effects of endogenous adrenomedullin on cardiac hypertrophy, fibrosis, and renal damage. Circulation 109: 1789-1794, 2004

11月 1日 海藤

Lai RC, Arslan F, Lee MM, Sze NS, Choo A, Chen TS, Salto-Tellez M, Timmers L, Lee CN, EI Oakley RM, Pasterkamp G, de Kleijin DP, Lim SK: Exosomes secreted by MSC reduces myocardial ischemia/reperfusion injury. Stem Cell Research 4: 214-222, 2010

10月27日 宮原

Leelahavanichkul A, Huang Y, Hu X, Zhou H, Tsuji T, Chen R, Kopp JB, Schnermann J, Yuen PS, Star RA: Chronic kidney disease worsens sepsis and sepsis-induced acute kidney injury by releasing High Mobility Group Box Protein-1. Kidney Int. 2011 doi: 10.1038/ki.2011.261 .

10月20日 重村

Lee YJ, Chang JW, Yang SW, Kim SB, Park SK, Park JS, Lee SK. Albumin-induced epithelial-mesenchymal transition and ER stress are regulated through a common ROS-c-Src kinase-mTOR pathway: effect of imatinib mesylate. Am J Physiol 300: F1214-F1222, 2011

10月13日 押川

Moon PG, You S, Lee JE, Hwang D, Baek MC: Urinary exosomes and proteomics. Mass Spectrom Rev doi: 10.1002, 2011

10月6日 髙橋

Ferreira L, Quiros Y, Sancho-Martinez SM, Garcia-Sanchez O, Raposo C, Lopez-Novoa JM, Gonzalez-Buitrago JM, Lopez-Hernandez FJ: Urinary levels of regenerating islet-derived protein IIIβ and gelsolin differentiate gentamicin from cisplatin-induced acute kidney injury in rats. Kidney Int 75: 518-528, 2011

9月28日 東島

Stodkilde L, Norregaard R, Fenton RA, Wang G, Knepper MA, Frokiare J: Bilateral ureteral obstruction induces early downregulation and redistribution of AQP2 and phosphorylated AQP2. Am J Physiol Renal Physiol: F226-F235, 2011

9月27日 西村

Orc L, Ravazzola M, Le Coadic M, Shen WW, Demaurex N, Cosson P: STIM1-induced precortical and cortical subdomains of the endoplasmic reticulum. Proc Natl Acad Sci U S A 106: 19358-19362, 2009

7月21日 園田

Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC: Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Proteomics 11: 2459-75, 2011

7月14日 池田

Role of T cells in hypertension
<論文1>Harrison DG, Guzik TJ, Lob HE, Madhur MS, Marvar PJ, Thabet SR, Vinh A, Weyand CM: Inflammation, immunity, and hypertension. Hypertension 57: 132-140, 2011
<論文2> Guzik TJ, Hoch NE, Brown KA, McCann LA, Rahman A, Dikalov S, Goronzy J, Weyand C, Harrison DG: Role of the T cell in the genesis of angiotensinII induced hypertension and vascular dysfunction. J Exp Med 204: 2449-2460, 2007

7月 5日

Yakata K, Tani K, Fujiyoshi Y: Water permeability and characterization of aquaporin-11. J Struct Biol 174: 315-320, 2011

6月28日 田畑

Shah KG, Rajan D, Jacob A, Wu R, Krishnasastry K, Nicastro J, Molmenti EP, Coppa GF, Wanq P: Attenuation of renal ischemia and reperfusion injury by human adrenomedullin and its binding protein. J Surg Res 163: 110-117, 2010

6月21日 海藤

Zhang Y, Li Y, Qiu F, Qiu Z: Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS. Electrophoresis 31: 3797-3807, 2010

6月 9日 押川

Stamer WD, Hoffman EA, Luther JM, Hachey DL, Schey KL: Protein profile of exosomes from trabecular meshwork cells. J Proteomics. 16: 796-804, 2011

6月 2日 宮原

Kim M, Park SW, Kim M, D’Agati VD, Lee HT: Isoflurane activates intestinal sphingosine kinase to protect against bilateral nephrectomy-induced liver and intestine dysfunction. Am J Physiol Renal Physiol 300: F167-F176, 2011

5月26日 重村

Cai Q, K. Nelson S, R. McReynolds M, Keck Diamond-Stanic M, Elliott D, L. Brooks H. Vasopressin increases expression of UT-A1, UT-A3, and ER chaperone GRP78 in the renal medulla of mice with a urinary concentrating defect. Am J Physiol Renal Physiol 299: F712-F719, 2010

5月19日 東島

Cheng CF, Lian WS, Chen SH, Lai PF, Li HF, Lan YF, Cheng WT, Lin HF: Protective Effect of Adiponectin against Renal Ischemia-Reperfusion Injury via Prostacyclin-PPARα-Heme Oxygenase-1 Signaling Pathway. J Cell Physiol DOI: 10.1002/jcp.22726, 2011

5月12日 西村

Walsh CM, Chavanov M, Haynes LP, Petersen OH, Tepikin AV, Burgoyne RD: Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry. Biochem J 425: 159-168, 2010

4月28日 髙橋

Hammer E, Goritzka M, Ameling S, Darm K, Steil L, Klingel K, Trimpert C, Herda LR, Dorr M, Kroemer HK, Kandolf R, Staudt A, Felix SB, Volker U. Characterization of the human myocardial proteome in inflammatory dilated cardiomyopathy by label-free quantitative shotgun proteomics of heart biopsies. J Proteome Res. 2011 Apr 1. DOI: 10.1021/pr1008042

4月19日 園田

Bouley R, Lu HAJ, Nunes P, Silva ND, McLaughlin M, Chen Y, Brown D: Calcitonin has a vasopressin-like effect on aquaporin-2 trafficking and urinary concentration. J Am Soc Neph 22: 59-72, 2011

4月13日 池田

Hetero-oligomerization between plant aquaporin molecules
Otto B, Uehlein N, Sdorra S, Fischer M, Ayaz M, Belastegui-Macadam X, Heckwolf M, Lachnit M, Pede N, Priem N, Reinhard A, Siegfart S, Urban M, Kaldenhoff R.(2010). Aquaporin tetramer composition modifies the function of tobacco aquaporins. J Biol Chem. 285, 31253-31260
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