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2014  
月日 担当者 Paper
2月26日 樺山

Pisitkun T, Gandolfo MT, Das S, Knepper MA, Bagnasco SM: Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. Proteomics Clin 6: 268-78, 2012

2月26日 星野

Inouse Y, Sohara E, Kobayashi K, Chiga M, Rai T, Ishibashi K, Horie S, Su X, Zhou J, Sasaki S, Uchida S: Aberrant glycosylation and localization of polycystin-1 cause polycystic kindney in an AQP11 knockout model. J Am Soc Nephrol 25: 2789-2799, 2014

 1月29日 Asvapromtada

Stodkilde L, Norregaard R, Fenton RA, Wang G, Knepper MA, Frokiaer J: Bilateral ureteral obstruction induces early downregulation and redistribution of AQP2 and phosphorylated AQP2. Am J Physiol Renal Physiol 301: F226-235, 2011

 1月22日 園田

Yu B, Kim HW, Gong M, Wang J, Millard RW, Wang Y, Ashraf M, Xu M: Exosomes secreted from GATA-4 overexpressing mesenchymal stem cells serve as a reservoir of anti-apoptotic microRNAs for cardioprotection. Int J Cardiol 23: 349-360, 2014

 1月15日 池田

<論文>Edinger RS, Coronnello C, Bodnar AJ, LaFramboise WA, Benos PV, Ho J, Johnson JP, Butterworth MB: Aldosterone refulates microRNAs in the cortical collecting duct to alter sodium transport. J Am Soc Nephrol 25: 2445-2457, 2014

12月11日 樺山

Fu Y, Sun Z, Fuchs EJ, Wang Y, Shen ZY, Maeda H, Lin Q, Warren DS, Williams GM, Montgomery RA: Successful transplantation of kidny allografts in sensitized rats after syngeneic hematopoietic stem cell transplantation and fludarabine. Am J Transplant 14: 2375-83, 2014

12月4日 星野

Muntean BS, Jin X, Williams FE, Nauli SM: Primary cilium regulates CaV1.2 expression through Wnt signaling. J Cell Physiol 229: 1926-1934, 2014

11月6日 Asvapromtada

Ryu HM, Oh EJ, Park SH, Kim CD, Choi JY, Cho JH, Kim IS, Kwon TH, Chung HY, Yoo M, Kim YL: Aquaporin 3 expression is up-regulated by TGF-β1 in rat peritoneal mesothelial cells and plays a role in wound healing. Am J Pathol 181: 2047-2057, 2012

10月30日 園田

Spanu S, van Roeyen CR, Denecke B, Floege J, Muhlfeld AS: Urinary exosomes: a novel means to non-invasively assess changes in renal gene and proteinexpression. PLoS One 9: e109631, 2014

10月23日 池田

<論文1>Radin, M. J., Yu, M. J., Stoedkilde, L., Miller, R. L., Hoffert, J. D., Frokiaer, J., et al. (2012). Aquaporin-2 regulation in health and disease. Veterinary Medicine and Science, 41, 455-470.
<論文2>Kortenoeven, M. L. A., & Fenton, R. A. (2014). Renal aquaporins and water balance disorders. Biochimica et Biophysica Acta, 1840, 1533-1549.

 
9月30日 木内

Peake PW, Pianta TJ, Succar L, Fernando M, Pugh DJ, McNamara K, Endre ZH: A comparison of the ability of leves of urinary biomarker proteins and exosomal mRNA to predict outcomes after renal transplantation. PLoS One Jun; 9(2):e98644, 2014

9月30日 加藤

Han J, Back SH, Hur J, Lin YH, Gildersleeve R, Shan J, Yuan CL, Krokowski D, Wang S, Hatzoglou M, Kilberg MS, Sartor MA, Kaufman RJ: ER-stress-induced transcriptinal regulation increases protein synthesis leading to cell death. Nat Cell Biol: 481-490, 2013

7月17日 樺山

Ono T, Nishijima H, Adachi N, Iiizumi S, Morohoshi A, Koyama H, Shibahara K: Generation of tetracycline-inducible conditional gene knockout cells in a human Nalm-6 cell line. J Biotechnol 141: 1-7, 2009

7月10日 木内

Lv LL, Cao YH, Ni HF, Xu M, Liu D, Liu H, Chen PS, Liu BC: MicroRNA-29c in urinary exosome/microvesicle as a biomarker of renal fibrosis. Am J Physiol Renal Physiol 305:F1220-F1227, 2013

6月10日 星野

<論文1>Chang MY, Ong AC: Endothelin in polycystic kidney disease. Contrib Nephrol 172: 200-209, 2011
<論文2>Maixnerova D, Merta M, Reiterova J, Stekrova J, Rysava R, Obeidova H, Viklicky O, Potmesil P, Tesar V: The influence of three endothelin-1 polymorphisms on the progression of IgA nephropathy. Folia Biol 53: 27-32, 2007

5月22日 加藤

Abreu-Rodriguez I, Sanchez SR, Martins AP, Soveral G, Toledo-Aral JJ, Lopez-Barneo J, Echevarria M: Functional and transcriptional induction of aquaporine-1 gene by hypoxia; analysis of promoter and role of Hif-1α. PLoS One 6: e28385, 2011

 
5月15日 Asvapromtada

Ikarashi N, Baba K, Ushiki T, Kon R, Mimura A, Toda T, Ishii M, Ochiai W, Sugiyama K: The laxative effect of bisacodyl is attributable to decreased aquaporin-3 expression in the colon induced by increased PGE2 secretion from macrophages. Am J Physiol Gastrointest Liver Physiol 301: G887-G895, 2011

4月24日 園田

Phuyal S, Hessvik NP, Skotland T, Sandvig K, Llorente A: Regulation of exosome release by glycosphingolipids and flotillins. FEBS J doi: 10.1111/febs.12775, 2014

4月17日 池田

<論文1>Esteva-Font C, Jin BJ, Verkman AS: Aquaporin-1 gene deletion reduces breast tumor growth and lung metastasis in tumor-producing MMTV-PyVT mice. FASEB J 28: 1446-1453, 2014
<論文2>Tan M, Shao C, Bishop JA, Feng Z, Trock BJ, Westra WH, Ha PK: Aquaporin-1 Promoter Hypermethylation Is Associated with Improved Prognosis in Salivary Gland Adenoid Cystic Carcinoma. Otolaryngol Head Neck Surg, doi: 10.1177/0194599814521569