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2023  
月日 担当者 Paper
2月13日

Yamagata S, Talukder AH, Murasawa S, et al. Vasopressin Expressed in Hypothalamic CRF Neurons Causes Impaired Water Diuresis in Secondary Adrenal Insufficiency. Endocrinology. 2023; 164(8):bqad109. doi: 10.1210/endocr/bqad109

2月1日 園田

A1- Bataineh MM, Sutton TA, Hughey RP: Novel roles for mucin 1 in the kidney. Curr Opin Nephro1 Hypertens. 26:384-391, 2017

1月25日 内村

Cheng Q, Shah N, Broer A, Fairweather S, Jiang Y, Schmoll D, Corry B, Broer S:Identification of novel inhibitors of the amino acid transporter B(0)AT1(SLC6A19), a potential target to induce protein restriction and to treat type 2 diabetes. Br J Pharmacol 174: 468-482, 2017

1月18日 小口

Taylor KM, Au AYM, Herath S, Succar L, Wong J, Erlich JH, Endre ZH: Kidney functional reserve and damage biomarkers in subclinical chronic kidney disease and acute kidney injury. Am J Physiol Renal Physiol 1: 888-898, 2023

12月21日 東島

Katzenelenbogen Y, Dahl SL, Shehan F, Gurevich-Shapiro A, Zada M, Phan TS, Avellino R, Wang SY, Barboy O, Shlomi-Loubaton S, Winning S, Markwerth PP, Dekalo S, Keren-Shaul H, Kedmi M, Sikora M, Fandrey J, Korneliussen TS, Prchal JT, Rosenzweig B, Yutkin V, Racimo F, Willerslev E, Gur C, Wenger RH, Amit I: The transcriptional and regulatory identity of erythropoietin producing cells. Nat Med, 29: 1191-1200, 2023 10.1038/s41591-023-02314-7

12月7日 園田(美)

Charles S, Sussenberger R, Settje T, Langston C, Lainesse C: Use of molidustat, a hypoxiainducible factor prolyy hydroxylase inhibitor, in chronic kidney disease-associated anemia in cats. J Vet Intern Med 2023, doi:10.1111/jvim.16807.

11月10日 池田

腎泌尿器の生理機能

10月19日 上間

Chao L, Jing G, Yunxiao K, Heming X, Ying C, Bao D, Kunshen L: Inhibition of dehydration-induced water intake by glucocorticoids is associated with activation of hypothalamic natriuretic peptide receptor-A in rat. PLOS ONE5 : 12, 2010

10月10日 髙山

Rush BM, Bondi CD, Stocker SD, Barry KM, Small SA, Ong J, Jobbagy S, Stolz DB, Bastacky SI, Chartoumpekis DV, Kensler TW, Tan RJ: Genatic or pharmacologic Nrf2 activation increases proteinuria in chronic kidney disease in mice. Kidney Int 99: 102-116, 2021

10月3日 川口

Tingskov SJ, Hu S, Frøkiær J, Kwon TH, Wang W, Nørre-gaard R:Tamoxifen attenuates development of lithium-induced nephrogenic diabetes insipidus in rats. Am J Physiol Renal Physiol 314: F1020-F1025, 2018.

7月20日 髙山

Zhang Y, Knatko EV, Higgins M, Dayalan SN, Smith G, Honda T, de la Vega L, Dinkova-Kostova AT: Pirin, an Nrf2-regulated protein, is overexpressed in human colorectal tumors. Antioxidants 11: 262, 2022

7月13日 川口

Zheng P, Lin Y, Wang F, Luo R, Zhang T, Hu S, Feng P, Liang X, Li C, Wang W: 4-PBA improves lithium-induced nephrogenic diabetes insipidus byattenuating ER stress. Am J Physiol Renal Physiol 311: F763-F776, 2016

7月6日 上間

Robert LT, Beltz TG, Johnson AK. Glucocorticoids increase salt appetite by promoting water and sodium excretion. Am J Physiol Regul Integr Comp Physiol. 2007; 293(3):R1444-1451. doi: 10.1152/ajpregu.00294.2007

7月6日 園田(美)

Grampp S, Kruger R, Lauer V, Uebel S, Knaup KX, Nass J, Hoffken V, Weide T, Schiffer M, Naas S, Schodel J: Hypoxia hits APOL1 in kidney. Kidney Int 104: 53-60, 2023

6月22日 神崎

Pajenda S, Wagner L, Gerges D, Herkner H, Tevdoradze T, Mechtler K, Schmidt A, Winnicki W: Urinary collectrin (TMEM27) as novel marker for acute kidney injury. Life.2022; 12:1391

6月15日 小口

Enoksen ITT, Rinde NB, Svistounov D, Norvik JV, Solbu MD, Eriksen BO, Melsom T: Validation of eGFR for detecting associations between serum protein biomarkers and subsequent GFR decline. J AM Soc Nephro l00: 1-12, 2023

6月8日 内村

Chu PL, Gigliotti JC, Cevhova S, Bodonyi-Kovacs G, Chan F, Ralph DL, Howell N, Kalantari K, Klibanov AL, Carey RM, McDonough AA, Le TH: Renal collectrin protects against salt-sensitive hypertension and is downregulated by angiotensin Ⅱ. J An Soc Nephrol 28: 1826-1837, 2017

6月1日

Chen M, Cai H, Klein JD, Laur O, Chen G: Dexamethasone increases aquaporin-2 protein expression in ex vivo inner medullary collecting duct suspensions. Front Phisiol 6: 310, 2015

5月25日 東島

Hurwitz B, Luo JD, Tseng T, Gur-Cohen S, Sribour M, Omelchenko T, Levorse J, Pasolli HA, Thompson CB, Mucida D, Fuchs E: A tissue injury sensing and repair pathway distinct from host pathogen defense. Cell, 186: 2127-2143 e2122, 2023 10. 1016/j.cell.2023.03.031

5月18日 園田

Sun Q, Zeng C, Du L, Dong C: Mechanism of circadian regulation of the NRF2/ARE pathway in renal ischemia-reperfusion. Exp Ther Med21: 190, 2021

5月11日 池田

Dai C, Charlestin V, Wang M, Walker ZT, Miranda-Verga MC, Facchine BA, Wu J, Kaliney WJ, Dovichi NJ, Li J, Littlepage LE: Aquaporin-7 regulates the response to cellular stress in breast cancer. Cancer Res 2020; 80: 4071-4086, 2020

4月27日 内村

TMEM27ノックアウトラットを用いた腎性ファンコーニ症候群発症メカニズムの検討

4月27日 小口

患者データを用いた簡便な尿流量推定方法についての検討

4月20日 髙山

bardoxolone methyl の薬理学的バイオマーカーとしての尿エクソソーム中 pirin の有用性の検討

4月20日 上間

合成副腎皮質ホルモン製剤のラットにおける利尿作用に関する研究

4月20日 川口

尿中細胞外小胞中のリン酸化AQP-2によるバゾプレシン活性の推測